Dr. Allan Wiik
Dr. Allan Wiik
ICAP认可已故的Allan Wiik博士(1936年12月- 2022年10月)对自身抗体实验室检测和报告单标准化和统一化所做出的重要贡献。
Allan Wiik博士是国际免疫学会联盟(IUIS) ANA小组委员会的创始成员和副主席(1-5)，欧洲自身抗体共识小组副主席和欧洲自身免疫标准化倡议委员会(EASI)主席(6)。他也是一位坚持推行ANA标准化的推动者(7)，并倡导患者、临床医生以及实验室科学家等各个方面的人员共同参与ANA标准化的推动(8-10)。
他使用先进的成像技术和算法使HEp-2 IFA荧光核型的命名和报告标准化是具有开创性的(11)，这对ICAP的工作至关重要(12)。他敏锐的思维、深厚的学术造诣将永远被我们铭记。
1.Tan EM, Feltkamp TE, Smolen JS, Butcher B, Dawkins R, Fritzler MJ, Gordon T, Hardin JA, Kalden JR, Lahita RG, Maini RN, McDougal JS, Rothfield NF, Smeenk RJ, Takasaki Y, Wiik A, Wilson MR, Koziol JA. Range of antinuclear antibodies in "healthy" individuals. Arthritis Rheum. 1997;40:1601-11.
2.Tan EM, Smolen JS, McDougal JS, Butcher BT, Conn D, Dawkins R, Fritzler MJ, Gordon T, Hardin JA, Kalden JR, Lahita RG, Maini RN, Rothfield NF, Smeenk R, Takasaki Y, van Venrooij WJ, Wiik A, Wilson M, Koziol JA. A critical evaluation of enzyme immunoassays for detection of antinuclear autoantibodies of defined specificities. I. Precision, sensitivity, and specificity. Arthritis Rheum. 1999;42:455-64.
3.Tan EM, Smolen JS, McDougal JS, Fritzler MJ, Gordon T, Hardin JA, Kalden JR, Lahita RG, Maini RN, Reeves WH, Rothfield NF, Takasaki Y, Wiik A, Wilson M, Koziol JA. A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. II. Potential for quantitation of antibody content. J Rheumatol. 2002;29:68-74.
4.Fritzler MJ, Wiik A, Tan EM, Smolen JS, McDougal JS, Chan EKL, Gordon TP, Hardin JA, Kalden JR, Lahita RG, Maini RN, Reeves WH, Rothfield NF, Takasaki Y, Wilson M, Byrd MG, Slivka L, Koziol JA. A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. III. Comparative performance characteristics of academic and manufacturers' laboratories. J Rheumatol. 2003;30:2374-81.
5.Chan EKL, Fritzler MJ, Wiik A, Andrade LE, Reeves WH, Tincani A, Meroni PL. Autoantibody Standardization Committee in 2006. Autoimmun Rev. 2007;6:577-80.
6.Damoiseaux J, Olschowka N, Shoenfeld Y. EASI - European Autoimmunity Standardisation Initiative: facing the challenges of diagnostics in autoimmunity. Clin Chem Lab Med. 2018;56:1620-3.
7.Bossuyt X, Louche C, Wiik A. Standardisation in clinical laboratory medicine: an ethical reflection. Ann Rheum Dis. 2008;67:1061-3.
8.Fritzler MJ, Wiik A, Fritzler ML, Barr SG. The use and abuse of commercial kits used to detect autoantibodies. Arthritis Res Ther. 2003;5:192-201. PMC:165068.
9.Wiik AS, Gordon TP, Kavanaugh AF, Lahita RG, Reeves W, van Venrooij WJ, Wilson MR, Fritzler M. Cutting edge diagnostics in rheumatology: the role of patients, clinicians, and laboratory scientists in optimizing the use of autoimmune serology. Arthritis Rheum. 2004;51:291-8.
10.Wiik AS. Anti-nuclear autoantibodies: clinical utility for diagnosis, prognosis, monitoring, and planning of treatment strategy in systemic immunoinflammatory diseases. Scand J Rheumatol. 2005;34:260-8.
11.Wiik AS, Hoier-Madsen M, Forslid J, Charles P, Meyrowitsch J. Antinuclear antibodies: a contemporary nomenclature using HEp-2 cells. J Autoimmun. 2010;35:276-90.
12.Chan EKL, Damoiseaux J, Carballo OG, Conrad K, de Melo Cruvinel W, Francescantonio PL, Fritzler MJ, Garcia-De La Torre I, Herold M, Mimori T, Satoh M, von Muhlen CA, Andrade LE. Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014-2015. Front Immunol. 2015;6:412. PMC:4542633.