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AC-XX-Type 3 nuclear pleomorphic pattern;AC-XX 3型核多形性型

同义词 抗-MSA2型(注意:不可与CENP-F(AC-14)型混淆) Anti-MSA2 pattern (Not to be confused with CENP-F (AC-14) pattern)
描述 核细/粗颗粒染色在不同细胞核间强度不一致。偶见核仁染色。分裂末期细胞中细胞间桥(桥主体)着色。后期末阶段细胞间桥前体上观察到早期染色。仅在中期的染色体着丝粒呈现粗颗粒染色。 Variable-intensity fine/coarse nuclear speckled. Occasional nucleolar staining. Staining of the inter-cellular bridge (stem body) sparing the midbody at telophase. Early staining of the stem body precursor in late anaphase. Coarse staining of centromeres exclusively at metaphase.
抗原相关性 可能为染色体乘客蛋白复合体(PCP)组分,如Aurora激酶B、INCENP或Survivin等 Variable-intensity fine/coarse nuclear speckled. Occasional nucleolar staining. Staining of the inter-cellular bridge (stem body) sparing the midbody at telophase. Early staining of the stem body precursor in late anaphase. Coarse staining of centromeres exclusively at metaphase.
  • 临床相关性

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    Clinical Relevance

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  • 一级信息参考文献
    First level information references
  • Humbel RL. GEAI online. https://www.geai-lesautoanticorps.fr/downloader.php?fname=docs/documents/Ac-anti-cellules-proliferatives-1616501218.pdf

    Humbel RL. GEAI online. https://www.geai-lesautoanticorps.fr/downloader.php?fname=docs/documents/Ac-anti-cellules-proliferatives-1616501218.pdf

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